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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b64e7d7b1061531f9de4a54671299ae0d0e135cee65bb43d3ac85a5599b52b3' 
  AND token = 'lCAKW4NBTJN+6a6yyZEv2s524p5c1aMLWpAHcmF7/t4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}