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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd7b12277ba2aa5157dd185de7c6e242b70ca8f95b369d22fb75291e3aebd0fd6' 
  AND token = 'fWzt/Wzv0wF6MRqpk1v5z9bFWbdpHyjrA7W6qBcFA0E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}