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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed92e1594b4d8d13b5d1d0b4abd21ea4d968742a9690906c02a373178ed08b84' 
  AND token = 'EoUrH1v/Wn0C0qMQB9VPEexmp3y9Cje//hhEVbJ4YkE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}