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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0121b8876b48cb078f23d77087a5db2c6c56b978cc81bec1a9ae5b6e06de9c6' 
  AND token = '3ccugjoT/SlAALikFFlEnzrHVjPsgev0QfN2nkAsStw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}