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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6fae59c6ad4cdef55f887eb924f7e66b68184194632d4133157d67ee8dffd26' 
  AND token = 'UReN/c/fek/7zoUCpB+nJ2VpBRvf5TI4hIkd3g++cNc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}