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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd1018281eb6fbc53f90c5eabeff8a52b21d98070cb01c845bcb8fb6485dd360' 
  AND token = '3+eOqETIsw4SWYEAxrVbkDxi726i9PCi/AvRnN2x5vo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}