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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2c2369f7c5b60d123d211bc66c023fa11a87ddfe75857fab27ab8b1bb24bb43' 
  AND token = 'H0zY2GTXpmq5JNEs4/oUOlt2Vs5Hq1T0/KwUAvcvp14=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}