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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8666fedbf8473a3a620f5142241be65ba01ac82ad6039b3bc2810d471344e57' 
  AND token = '6aVFXbdiH+c4n4BeAhQ3Kc1UCd4eo26Ese7qEr7XOZk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}