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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27eba6ebcced68455a6c421dec9f0ff36b6f98813804c0781f91d5b303e392a4' 
  AND token = 'kgoF0x5dbO3nxwBAUPJW85feNsdA8p5GSV8vwfoTrMI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}