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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f035935ec60f8f7df9426db06aa073990e26b17b6f0c02e925dc4fbd9bf7145' 
  AND token = 'Eu74A+GZuz0igdrgvQt49A7KUhqb6w+Hb7FeaOCZIQU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}