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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de851682f99eb94c517544176c646bbf79d34fef059f93c446557b55dc14001d' 
  AND token = 'II8FfwRLwFr+efhyLeMK63YcN2XMAlyBB2/3p0g0XvI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}