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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a53e930e7fefb5e7de737950a17113f14682d185b7282dd97c2e441a8e7a4189' 
  AND token = 'dXmsk16Oirn9wCsMbo6e/QdvlYTlA+V8rOVOjK1sdRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}