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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af6aebe32b8a73344162d27fdce5a5cc0cf10b17335f54b5240d007d9b14ae75' 
  AND token = 'W3PbSbqqRCcjRpNXDQVMwHjjDMjmd6QMAiWJuGNJF/8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}