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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '319d82b056151d96c8dfc5a8eff3ede69bb43f85e5bb68d08a1e14b6365dd72c' 
  AND token = 'EzPAvM9X5x0buGAuOeSBLUB5qSp2t2mH9zVLWX+vQJs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}