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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5e087d80d8e1494b24ccda62ff01af975e3d26734f9b47feaa8e6e207629040' 
  AND token = '2PG8axglfwmtxowiPSCbPGnqGzMrF10kk7KU5Pg0WWM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}