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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d5b9aefe62a4fee50a687d558c5760554c3ea927c1124131fa0a160c235b9d9' 
  AND token = 'eb2BxFsmP1l8/NBd2J4O2AZOSiXOLQR4uVCk7B7gVLs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}