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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '781d4cee7c41f7577c5189e6e634dcd7125ec4174a3fb70b5696f0fc8c6b01b5' 
  AND token = 'Bx5xBsJIxCibpSuM8r7I8Fi8/BU9ZvRZ7idDMNH8+24=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}