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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c28ba8e197298101e3e7a20580a29d87b5e6158ae827485f195d45af9e315803' 
  AND token = 'SkTH588ZWk7NwMNUtOdisQYGDyHN0/XiM4+PKp/3SdE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}