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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06de0e339397a44333a0d58c3518f91757b7c09b1485293236e5d7592e3a0683' 
  AND token = 'Ui+WcH0X1dTPhk8P7LGuHEFxDoFZbDFFyf6fhr3QXCM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}