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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29651330bce6e3b1f1245adb0a5c473069d0987622e4881012f825788d02287a' 
  AND token = 'yyfXo6ff9TIyr2YTSQVKZ0yzrjarXEWX0jsOZHxaW+4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}