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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed65a210daf222a28a389338120c7ca76fa2f9167eb7a66716a8585a249c9c30' 
  AND token = 'Bc7RnnCAzoS7MmHPiJUNB7CWIBx2ZW/L5zY7bCkJXzQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}