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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3176f1358c5effa08e7b44e4a9d5225340bffa0e4e4fee48d4228a2fe703c129' 
  AND token = '8inMBndGEp6+7s9XL67y9E92K7FKX5apeV2HIc40t+g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}