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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '430c538f6509caf0451454613667e76d8933b2210c6322506d90eaffc1e5e5c3' 
  AND token = 'JvMSOifUUlNI3TwBELPtSNATb/+scU9n6tUdcY/l7SI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}