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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da6735f3a0a92e442d3d242d3ed949dc633c4f376980dcfc7cf674b6b55b6600' 
  AND token = 'O+udbY0L9Z/3aEMr0cIQo2ST7a2N/dxhPLCI9XFsA3E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}