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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fb251d6838088f11d4e9c493ea0b5ba8c283f484a0b3b63674f694a404ffb4b' 
  AND token = 'CY5MBKhCG+1co1/JltMy7D+9tw9wTLlMeMp7Xt+60aI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}