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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd84a538e11dbf061f78fcd414b05021518b6f9a875e7b62345bb65a3bb87940' 
  AND token = '78QkBU9QqNa/xluOr+I0sr9+bh+tdliU2P6a7vByLhw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}