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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c05480b3f1c81fe999be8dbc9a1b78651977fe372c1ba2edadacf06a5c7dd65b' 
  AND token = 'YBHcHP/RDAGuqPjH06+UMzxrsyt9Ysv7hX20wtaSvAo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}