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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a16a4472c379eaeae27cc41a35a23303b619666e74ef64f2d4f2ef78d883ba9' 
  AND token = 'vFTFDUGct6XS1ovtLpq9LC+qX5A+AtH9ehR0c4/6/3o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}