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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80629848e826c2bb6965721edfc22f506f6d8e9c09169870c946db3ee1c045c8' 
  AND token = '7dcoNJtoOvnTU1vZ9S5dCouylM5Xpj6AYg3278+Qyzg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}