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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0f27a5dc3846cdf7e08b1a750be9b3f9f00eb353f309a61c065fe5017fe2d30' 
  AND token = 'ZhVRshd7SmIWXPXnxPsk9WVKrDu9Nr6F2tX+aFZbM0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}