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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42061ed5ca7f173fbf62d85b5747dbcc7bc34744ffb4826819e5c8cef6484702' 
  AND token = 'pQcHVGLtBaREncSC5xhNHnVneVEyTi4L7tfMh3ozQEA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}