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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6baa857807ac0d1fdded2f187aaeb13cbdcedbbeb0ed309afe1c50f9c1280169' 
  AND token = 'iMi3fweZxly79kIygAZ2Y+bDi1/5OBVCHRNrRfMD2sY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}