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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2aa78d4b3c08359bcb7fb08bd04d5cc08379116ba1b74e208b3598fe16e3fd8' 
  AND token = 'EtTqduWjayG8LVQT7CFNN6350XmPWHtvWmgNa8Wa9Lk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}