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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a41f5bac6ab61e00e20a0061f7372ec2cdb2d05a3fbea32fdaab4dcad7066d9' 
  AND token = 'qlU7bml+xhqiggt0AvYyEYUFWEu/dS+zCt7zoyz+Gx0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}