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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1023794f396ca1d07b0d663092d9c6a478aa9d136c2e8459f4268d7a8ff02b7f' 
  AND token = 'DVmKaMpQDrkrylfcIJryn4eUq5XW5KIujbk9SCiC27k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}