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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '211fd93537f98bb3c83f62bf00d59d37d786c3f2749c5ab702b996d63c4147d4' 
  AND token = '3jgsCk/kTHFvaiyMQzN1RpdE84GbD1GfpHNMaCZiLTM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}