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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f880a6f744a66a5233442f6ede55d1c9269fee4af98e4468aa3483b5d294c7af' 
  AND token = 'ED5My8NCzOd1y/+manwrN+Pc2xw9xVZavGO+d3zqCak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}