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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6658a43a0dcdebc840a40c6bf477d892b49e62b7d2399f1ab38e9c284e811d5' 
  AND token = 'CL8W0ueRhA6QYk/LZOpfMTpxFDTVujrXSRTKiT3CN78=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}