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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a3987e67cf62f1eb5d8f5ab6520b99b6b8c44624fb35b735390233a34064583' 
  AND token = 'gKoIOfBMhK1ubPcl6q000mWAg5YX2ACZb2/aLivnkk4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}