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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ff60a55273edf7fe8c560f40029d48efd8e8f66b99c980af979814d2005153a' 
  AND token = '+AYq2u9MKZ87ldqtGR6VTI+OFiWV5Fj1z0sGHArD5K8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}