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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d2eccc888ae761e4a00765e72038caffe5f7871f9312c30dd4f232ca9948eee' 
  AND token = '9b8aYMe+JsvACAj8f8WwkZs+TJQfKs3yr2TRnh8jEBo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}