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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7d3be5b38780242db4a0064b7b80a597e0fa5cc24cdd79de0b58c00fc434c17' 
  AND token = 'fhQyRpHkRCZGkQcg0lGWh5zq/ZScrRbW3eBgT8stFDM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}