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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cff76fa0d886999fff3cc3420da72175a1471fb2595ef2d221d7cc888ba3c6ab' 
  AND token = '5vXQkhyZjsxtRc9B2dennPN5cJHwdmTmhEUIOA57l3A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}