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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5a8af21874549fd8b1ac6bd75e3322d6e20a52511542f7849f5381af9604059' 
  AND token = 'R06Oym1qLTpgiced+4uc1/qnLTTfgFjuz8qM/EJDSGk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}