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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88fe4221a77f033528e5260ee0d7007342443f623df8c240fda489fef13a7215' 
  AND token = 'iBjmoBCTMrQ8iz9I9jPJXu/tno9Zvn4OVR0K/fQiG7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}