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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8fa9adfb4c0d17ef6b5405eeafe5c26c001db88a12f878dcec01c61783df2d5' 
  AND token = 'rx57Yyjj9syfRs4gRzYOEEY8Z9RT07/z98oOdk/N41Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}