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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '321d62062df4cbb1dc6e31aa7e87146c11666cf286fd22635bb5a0c48737d8ec' 
  AND token = '8PVZ1DyfCma8Yh4GY9bGSleWFJ91H31tTxH2YvDlBl8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}