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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a78d37848e01d6bb703ec8910ba8a88f078ead143838c20382dcbadb49d872b' 
  AND token = 'be6m+22lCt1YVWQ43l0xc7t7GakDygBj8YJAPpjCyH8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}