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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c6c157ca2980db22d678fbe5c4018ad6f981a3115c643bef8c1e241372a9414' 
  AND token = '/WWDhUf+wKwcRsyY31h87MvzSPNPGgPc9oas6mxQig4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}