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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8992aa29b7633bba471a7d534f31e6abdba0000817806c72b37d2c27b7daf652' 
  AND token = 'Zq5v1Md+ZLZayZyh+EkKHvsRA7ikxmkCyyk90pK4kFc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}